Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to.
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Gabapentin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
Stomatitis, gingivitis, perirectal inflammation, colitis, sinusitis, paronychia, and otitis gabapentin lab values often occur. Physical examination addresses the presence of splenomegaly and signs of other underlying disorder eg, arthritis, lymphadenopathy. The most commonly observed gabapebtin events associated lb the use of Neurontin in adults, not seen at an equivalent frequency among placebo-treated patients, were dizziness, somnolence, and peripheral edema. Patients with prolonged neutropenia after hematopoietic stem cell transplantation or chemotherapy and patients receiving high doses of corticosteroids are predisposed to fungal infections. To view content sources and attributions, please refer to our editorial policy.
For more information, ask your healthcare provider or pharmacist. Diagnosis is by WBC count with differential, but evaluation requires identification of the cause. Gabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. They normally have lower neutrophil counts but do not have increased risk of infection. Enter test name, test code, CPT or keyword. Antiepileptic drugs should not be abruptly discontinued because of the possibility of increasing seizure frequency.
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Differentiation between neutropenia caused by certain antibiotics and infection can sometimes be difficult. This information is not specific medical advice and does not replace information you receive from your health care provider. Acute, severe neutropenia, particularly if another factor eg, cancer is present, significantly impairs the immune system and can lead to rapidly fatal infections. Musculoskeletal and Connective Tissue Disorders. Neutropenia is also a feature of myelodysplasia , where it may be accompanied by megaloblastoid features in the bone marrow, and of aplastic anemia and can occur in dysgammaglobulinemia and paroxysmal nocturnal hemoglobinemia.